KINETICS AND MECHANISM FOR OXIME FORMATION FROM PYRIDINE-2-CARBOXALDEHYDE, PYRIDINE-3-CARBOXALDEHYDE, AND PYRIDINE-4-CARBOXALDEHYDE

Authors
MALPICA A CALZADILLA M BAUMRUCKER J JIMENEZ J LOPEZ L ESCOBAR G MONTES C
Citation
A. Malpica et al., KINETICS AND MECHANISM FOR OXIME FORMATION FROM PYRIDINE-2-CARBOXALDEHYDE, PYRIDINE-3-CARBOXALDEHYDE, AND PYRIDINE-4-CARBOXALDEHYDE, Journal of organic chemistry, 59(12), 1994, pp. 3398-3401
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
59
Issue
12
Year of publication
1994
Pages
3398 - 3401
Database
ISI
SICI code
0022-3263(1994)59:12<3398:KAMFOF>2.0.ZU;2-6
Abstract
Grime formation from pyridine-2-, -3-, and -4-carboxaldehydes occurs w ith rate-limiting carbinolamine dehydration under both acidic and neut ral conditions. Carbinolamine dehydration of pyridine-2-carboxaldehyde occurs via a transition state bearing a single positive charge, unlik e the corresponding reaction for formyl-1-methylpyridinium ion and the reaction under acidic conditions for pyridine-3- and -4-carboxaldehyd es.