The microcirculation of tooth buds at the bell stage obtained from 5-m
onth-old human fetuses was studied using corrosion casting and scannin
g electron microscopy. Each tooth bud has two independent vascular net
works: one of the enamel organ and one of the dental papilla. Both sys
tems are supplied by vertical branches of the inferior alveolar artery
. The vascular bed of the enamel organ consists of capillaries relativ
ely uniform in shape, forming a moderately dense network with irregula
r meshes. In contrast, the vasculature of dental papilla is extremely
dense and its vessels show a sinusoidal character and signs of a vivid
angiogenesis. The cast surfaces of capillaries in both vascular syste
ms show the presence of tiny blebs probably representing extravasation
s of the casting medium through endothelial fenestrations.