NEBULIZED SODIUM-BICARBONATE IN THE TREATMENT OF CHLORINE GAS INHALATION

Authors
Citation
Gm. Bosse, NEBULIZED SODIUM-BICARBONATE IN THE TREATMENT OF CHLORINE GAS INHALATION, Journal of toxicology. Clinical toxicology, 32(3), 1994, pp. 233-241
Citations number
27
Categorie Soggetti
Toxicology
ISSN journal
07313810
Volume
32
Issue
3
Year of publication
1994
Pages
233 - 241
Database
ISI
SICI code
0731-3810(1994)32:3<233:NSITTO>2.0.ZU;2-Z
Abstract
In this two year retrospective review, 86 cases of chlorine gas inhala tion from 49 medical facilities were treated with nebulized sodium bic arbonate on the recommendation of the Kentucky Regional Poison Center. Typical manifestations included cough, chest discomfort, shortness of breath, and wheezing. No patients developed pulmonary edema or respir atory insufficiency requiring ventilatory support. Sixty-three cases ( 73.3%) were exposures to chlorine producing acid/hypochlorite mixtures . Six (7.0%) were exposed to chlorine gas in industrial settings. Twel ve (14.0%) were exposed to chlorine gas in swimming pool settings. Six ty-nine (80.2%) were treated and released from the emergency departmen t. In 53 patients, clinical condition was clearly improved on emergenc y department discharge. Seventeen (19.8%) were admitted to the hospita l. All admitted patients gradually improved and had a mean hospital st ay of 1.4 days (range 1 to 3 days). No patients in this study deterior ated clinically after nebulized sodium bicarbonate use. Nebulized sodi um bicarbonate appears safe and merits prospective evaluation in the t herapy of chlorine gas inhalation.