IBUPROFEN OVERDOSE COMPLICATED BY RENAL-FAILURE, ADULT-RESPIRATORY-DISTRESS-SYNDROME, AND METABOLIC-ACIDOSIS

Authors
LE HT BOSSE GM TSAI YY
Citation
Ht. Le et al., IBUPROFEN OVERDOSE COMPLICATED BY RENAL-FAILURE, ADULT-RESPIRATORY-DISTRESS-SYNDROME, AND METABOLIC-ACIDOSIS, Journal of toxicology. Clinical toxicology, 32(3), 1994, pp. 315-320
Citations number
20
Categorie Soggetti
Toxicology
Journal title
Journal of toxicology. Clinical toxicology → ACNP
ISSN journal
07313810
Volume
32
Issue
3
Year of publication
1994
Pages
315 - 320
Database
ISI
SICI code
0731-3810(1994)32:3<315:IOCBRA>2.0.ZU;2-B
Abstract
Acute ingestion of ibuprofen commonly results in no symptoms, or minor gastrointestinal or central nervous system manifestations. While most cases of ibuprofen overdose do well, serious toxicity may occur, and is difficult to predict. A case of ibuprofen overdose is presented in which the course was complicated by metabolic acidosis, adult respirat ory distress syndrome, and renal failure necessitating prolonged dialy sis.