The enhanced toxicity of acid instilled directly into the rectum, with
out benefit of dilution and neutralization in the upper intestine, is
evident in a case of acetic acid intoxication by accidental rectal adm
inistration of 50 mL of 9% acetic acid to a 5-year-old boy. The compli
cations included necrosis of the colon, acute renal failure, acute liv
er dysfunction, disseminated intravascular coagulopathy (DIC) and seps
is.