S. Lippert et E. Gutschik, VIEWS OF CARDIAC-VALVE PROSTHESIS PATIENTS AND THEIR DENTISTS ON ANTICOAGULATION THERAPY, Scandinavian Journal of Dental Research, 102(3), 1994, pp. 168-171
By administering a questionnaire to 253 patients with cardiac-valve pr
ostheses (89.3% responding), and another to 136 of their attending den
tists (79% responding), the level of knowledge among both groups of an
ticoagulant therapy in connection with dental treatment was investigat
ed. The cardiothoracic department monitored all anticoagulation therap
ies. Of the anticoagulated patients, 96.6% were able to state their me
dication (94.1% received phenprocoumon); and of 86 dentists with patie
nts on anticoagulation treatment, 94% were aware of their patients' me
dication. All 20 dentists stating that their patients did not receive
anticoagulants were correct. The great majority (98%) of the dentists
employed a special measure to reduce the risk of bleeding associated w
ith invasive dental procedures, most commonly (86%) referring patients
to their general practitioner or hospital department for adjustment o
f the anticoagulant therapy. Around 60% of the dentists considered ext
ractions and operations to require measures to reduce the risk of blee
ding complications. We recommend referral of patients to the attending
physician for adjustment of anticoagulation to a target International
Normalized Ratio (INR) of 4.0 or possibly 3.0 before undergoing denta
l procedures involving the risk of bleeding. Additional reduction of t
he bleeding risk can be obtained by local application of an inhibitor
of fibrinolysis (tranexamic acid).