A survey of the 2075 cases in the Leeds Bone Tumour Registry showed th
at 54 cases of Primary Lymphoma of Bone that had been registered since
data collection began in 1958 (2.6% of primary bone tumours). The ove
rall sex ratio was 1.5 males: 1 female, largely due to the preponderan
ce of males in the under 40 age group. The age distribution was bimoda
l, the second peak of incidence demonstrating a significant reversal o
f the sex ratio with females being more commonly affected in the older
group. The clinical features and radiological findings were non-speci
fic, diagnosis relying principally on tissue histology. The overall su
rvival at five years was 46% and was not affected by the interval from
the onset of symptoms until the final diagnosis.