SECRETION OF MUCOPROTEINS IN A GALLBLADDE R WITH GALLSTONES

Secretion of mucoproteins or mucine (MP) have been studied as possible markers in several pathological conditions of the digestive tract, su ch us colonic poliposis or gastric dysplasia. In the gallbladder (VB) it has been established that form the core of crystalization for the c alculi. A study in 100 gallbladders have been made based on the utilit y of the analysis of the qualitative and quantitative modifications of MP in lithogenesis. It was been determined by histochemical technique s the three main types of MP (neutral, low and high sulphated add) to evaluate the alterations in the process of lithiasis. Results show a h igh production of the MP in VB with lithiasis, presenting in 97% a mix ed composition of MP (48.9% of 2 types, and 3 types in 46%), without a predominating type in this pathology.