CROSS-REACTIVITY OF MONOVALENT AND POLYVALENT TRIMERESURUS ANTIVENOMSWITH VENOMS FROM VARIOUS SPECIES OF TRIMERESURUS (LANCE-HEADED PIT VIPER) SNAKE

Authors
TAN NH CHOY SK CHIN KM PONNUDURAI G
Citation
Nh. Tan et al., CROSS-REACTIVITY OF MONOVALENT AND POLYVALENT TRIMERESURUS ANTIVENOMSWITH VENOMS FROM VARIOUS SPECIES OF TRIMERESURUS (LANCE-HEADED PIT VIPER) SNAKE, Toxicon, 32(7), 1994, pp. 849-853
Citations number
20
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Toxicon → ACNP
ISSN journal
00410101
Volume
32
Issue
7
Year of publication
1994
Pages
849 - 853
Database
ISI
SICI code
0041-0101(1994)32:7<849:COMAPT>2.0.ZU;2-8
Abstract
Trimeresurus bite is a serious medical problem in Asia. However, at pr esent only a few monospecific Trimeresurus antivenoms are available. I nvestigation of the cross-neutralization capacity of three Trimeresuru s antivenoms indicates that the antivenoms exhibit broad cross-reactiv ity. A polyvalent Trimeresurus antivenom was also found to be effectiv e in neutralization of the haemorrhagic, necrotizing and thrombin-like activities of heterologous Trimeresurus venoms.