FERRITIN STIMULATION OF A MONOKINE INHIBITOR OF LIPOPOLYSACCHARIDE-AUGMENTED MYELOPOIESIS IS FERROXIDASE DEPENDENT

Authors
KREISBERG R BROXMEYER HE MOORE RN
Citation
R. Kreisberg et al., FERRITIN STIMULATION OF A MONOKINE INHIBITOR OF LIPOPOLYSACCHARIDE-AUGMENTED MYELOPOIESIS IS FERROXIDASE DEPENDENT, Infection and immunity, 62(7), 1994, pp. 2991-2994
Citations number
18
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
62
Issue
7
Year of publication
1994
Pages
2991 - 2994
Database
ISI
SICI code
0019-9567(1994)62:7<2991:FSOAMI>2.0.ZU;2-M
Abstract
Ferritin inhibition of myelopoiesis has been associated with intrinsic ferroxidase activity of heavy-chain ferritin and with production of a monokine inhibitor of lipopolysaccharide (LPS)-augmented monocytopoie sis. We report here that intrinsic ferroxidase activity of heavy-chain ferritin is required for stimulated production of the monokine inhibi tor of LPS-augmented monocytopoiesis.