GROWTH TEMPERATURE REVERSIBLY MODULATES THE VIRULENCE OF LEGIONELLA-PNEUMOPHILA

Authors
MAUCHLINE WS JAMES BW FITZGEORGE RB DENNIS PJ KEEVIL CW
Citation
Ws. Mauchline et al., GROWTH TEMPERATURE REVERSIBLY MODULATES THE VIRULENCE OF LEGIONELLA-PNEUMOPHILA, Infection and immunity, 62(7), 1994, pp. 2995-2997
Citations number
35
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
62
Issue
7
Year of publication
1994
Pages
2995 - 2997
Database
ISI
SICI code
0019-9567(1994)62:7<2995:GTRMTV>2.0.ZU;2-3
Abstract
In chemostat culture, the virulence of two strains of Legionella pneum ophila was shown to be significantly (P < 0.05) reduced when the cultu re temperature was lowered from 37 to 24 degrees C. This modulation wa s reversed by returning the temperature to 37 degrees C, which resulte d in a statistically significant (P < 0.05) increase in virulence.