PALLADIUM-CATALYZED CHEMOSELECTIVE REACTION OF ALLYLIC CARBONATE WITHNUCLEOSIDE BASES AND ITS APPLICATION FOR THE SYNTHESIS OF CARBOCYCLICNUCLEOSIDES - (-)-CARBOVIRS AND (-CARBOVIRS())

Authors
NOKAMI J MATSUURA H NAKASIMA K SHIBATA S
Citation
J. Nokami et al., PALLADIUM-CATALYZED CHEMOSELECTIVE REACTION OF ALLYLIC CARBONATE WITHNUCLEOSIDE BASES AND ITS APPLICATION FOR THE SYNTHESIS OF CARBOCYCLICNUCLEOSIDES - (-)-CARBOVIRS AND (-CARBOVIRS()), Chemistry Letters, (6), 1994, pp. 1071-1074
Citations number
29
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
6
Year of publication
1994
Pages
1071 - 1074
Database
ISI
SICI code
0366-7022(1994):6<1071:PCROAC>2.0.ZU;2-P
Abstract
Palladium(0)-catalyzed reaction of 2-cyclopenten-1-yl methyl carbonate derivatives with nucleoside bases gave carbocyclic nucleosides chemo- and regioselectively under the neutral reaction conditions. The react ion was effectively used for the synthesis of (-)- and (+)-carbovir an d its analogues.