Capillary electrophoresis techniques offer high plate numbers and are
highly suited for the efficient separation of a wide variety of chemic
al components in diverse matrices. Because of the small capillary and
detection cell dimensions, together with the minute volumes of samples
to be injected, sensitive detection devices based on different physic
ochemical principles are being developed by various scientific groups
and companies. The nature, possible applications and limitations of ch
emiluminescence as a detection technique are outlined in the present m
anuscript. The technique so far has only been explored by a limited nu
mber of research groups, and serious developments are to be expected f
or the coming years.