2 CASES OF EPSTEIN-BARR PRIMARY INFECTION INITIATED BY MENINGOENCEPHALITIS

Two patients, 19 and 16 years old, were hospitalized with meningoencep halitis symptoms, initiated by a generalised epileptic crisis in one c ase and by a coma in the other case. None of the patients showed typic al signs of infectious mononucleosis. In both cases clinical improveme nt spontaneously occured within few days. These meningoencephalitis we re relied to an Epstein-Barr primary infection by a systematic Epstein -Barr virus (EBV) serology and, in one case, by the detection of EBV g enome in the CSF. The value of viral genome presence in the CSF need t o be discussed.