Purpose: Multiple evanescent white dot syndrome (MEWDS) is usually uni
lateral, self-limited, and monophasic. The purpose of this study was t
o demonstrate that a chronic recurring form of the disease exists. Met
hods: Three patients with otherwise typical MEWDS were observed for 4
to 5 years. Their ocular histories and physical findings were recorded
. Results: Multiple recurrences (5-7) involving both eyes were noted i
n each of the three patients. Classic clinical findings were seen, inc
luding granularity to the macula, white dots, and optic disc changes.
Despite these recurrences, the patients still retained visual acuity o
f 20/20 in each eye. Conclusion: A chronic recurrent form of MEWDS exi
sts. The cause of MEWDS remains unknown, and it is unclear why these p
atients demonstrated this atypical clinical course.