The purpose of routine screening mammography is to detect unsuspected
cancer that has the potential to be cured. Abnormalities detected on t
he screening examination often necessitate additional radiologic worku
p before a definitive result or diagnosis can be given. This workup (d
iagnostic mammography) may include specialized views, such as spot com
pression to evaluate the margins of a nodule, or magnification views t
o determine the features of microcalcifications. Additional evaluation
with mammographic views, breast ultrasound, and, at times, interventi
onal procedures such as fine needle aspiration or core biopsy are perf
ormed to complete the radiologic evaluation of a patient with an abnor
mal mammogram. Signs of malignancy include nodules (most often poorly
defined), microcalcifications, and, less commonly, areas of architectu
ral distortion, asymmetry, of focal ductal dilatation. A comprehensive
approach to breast imaging will help to potentiate the early detectio
n of subtle malignancies and avoid the performance of some biopsies fo
r benign lesions.