P. Krailadsiri et J. Seghatchian, EFFECT OF FILTRATION, STORAGE AND PLATELET SUSPENSION MEDIA ON PLATELET INDEXES, Transfusion science, 15(2), 1994, pp. 179-183
We describe a new approach for assessing filtration-induced changes in
cellular indices of platelet concentrates at the beginning and the en
d of storage, using pairs of identical packs. The results revealed tha
t post-filtered products did not store as well as their counterparts.
Filtration did not induce any significant changes on aggregation as de
termined by spontaneous aggregation nor was there a disparity between
leucocyte peroxidase/basophil count. We recommend filtration on day 2
which causes minimal loss of platelets and less change in the mean pla
telet volume.