N-SUBSTITUTED PYRROLINONES FROM ENAMINES AND ALPHA-DICARBONYLS

Authors
CABALLERO E PUEBLA P DOMERCQ M MEDARDE M LOPEZ JL SANFELICIANO A
Citation
E. Caballero et al., N-SUBSTITUTED PYRROLINONES FROM ENAMINES AND ALPHA-DICARBONYLS, Tetrahedron, 50(26), 1994, pp. 7849-7856
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
26
Year of publication
1994
Pages
7849 - 7856
Database
ISI
SICI code
0040-4020(1994)50:26<7849:NPFEAA>2.0.ZU;2-8
Abstract
The reaction between N-substituted enamines and phenylglyoxal or glyox al yielded Delta(2)-pyrrolin-5-ones in moderate to good yields. An unc ommon pyrrolo [2,1-b]thiazole derivative was formed as a minor product when a N-(2-mercaptoethyl)enamine was used as the starting reagent. A n explanation for the regiochemistry of the reaction is proposed.