Sj. Millen et Dl. Daniels, THE EFFECT OF INTRACRANIAL SURGICAL TRAUMA ON GADOLINIUM-ENHANCED MAGNETIC-RESONANCE-IMAGING, The Laryngoscope, 104(7), 1994, pp. 804-813
Gadolinium-enhanced magnetic resonance im aging (MRI) is currently the
gold standard for diagnosis of an acoustic neuroma. Its status in dia
gnosis of a recurrent or residual neuroma is not nearly as clear. A pi
lot study of 36 postoperative cases showed enhancement in 100% of the
patients at the operative site. To examine the role of surgical trauma
and biodegradable packing on enhanced MRI, an animal study was design
ed. Cats and monkeys that under went posterior fossa surgical procedur
es had preoperative and postoperative MRI and histologic correlation o
f any enhanced area. Areas of postoperative enhancement should not be
considered as diagnostic of tumor. Further studies are necessary to de
velop a criteria for recurrent tumor diagnosis with enhanced MRI.