Tympanometry was performed before (preoperative) and after (intraopera
tive) the administration of inhalation anesthesia including nitrous ox
ide and halothane on 109 children undergoing myringotomy with pressure
equalization tube insertion. A total of 213 preoperative tympanograms
were compared with their intraoperative counterparts and the presence
or absence of middle ear effusion at myringotomy. When preoperative t
ympanograms were consistent with pneumatized middle ears, intraoperati
ve findings demonstrated a mean middle ear pressure increase of +147 d
aPa. When preoperative tympanometry suggested middle ear effusion, les
s than 1% demonstrated intraoperative tympanometric changes and/or fin
dings at surgery that would support anesthesia clearing middle ear eff
usion. Preoperative tympanometric data were poor predictors of the pre
sence or absence of effusion at myringotomy. The relationship between
inhalation anesthetics (i.e., nitrous oxide and halothane) and middle
ear fluids, and the reliability of tympanometry to predict middle ear
effusion are discussed.