From the human entropy production per surface area obtained in a previ
ous study, entropy productions per human individual of various ages ar
e calculated. It is shown that the entropy production increases from b
irth to about 16 years of age for males and to about 14 years of age f
or females, and then gradually decreases afterwards. Th is two-stage p
rinciple characteristic of entropy production (the early increase and
the later decrease) does not accord with the well-known minimum entrop
y production principle. The ''two-stage principle'' will be universall
y applied to aging over the life span of humans and other animals.