MODIFICATION OF ADRIAMYCINE CYCLOPHOSPHAMIDE INDUCED IMMUNE SUPPRESSION BY AN AMINOTHIOL/

Authors
BHANUMATHI P SALEESH EB VASUDEVAN DM
Citation
P. Bhanumathi et al., MODIFICATION OF ADRIAMYCINE CYCLOPHOSPHAMIDE INDUCED IMMUNE SUPPRESSION BY AN AMINOTHIOL/, Biochemical archives, 10(2), 1994, pp. 111-116
Citations number
7
Categorie Soggetti
Biology
Journal title
Biochemical archives → ACNP
ISSN journal
07495331
Volume
10
Issue
2
Year of publication
1994
Pages
111 - 116
Database
ISI
SICI code
0749-5331(1994)10:2<111:MOACII>2.0.ZU;2-A
Abstract
Cancer chemotherapeutic drugs are toxic to normal tissues and this tox icity is a limiting factor in the usage of higher doses. Another drwba ck of antineoplastic agents is their immunosuppressing nature. In the present study an aminothiol WR-1065 showed an antagonistic action agai nst the immunosuppressent nature of two commonly used anticancer drugs , cyclophosphamide and adriamycine.