DETECTION OF HYDROXYL FREE-RADICALS IN THE REPERFUSED PRIMATE HEART

Authors
PREMARATNE S SUEHIRO A SUEHIRO GT ARAKAKI HY MCNAMARA JJ
Citation
S. Premaratne et al., DETECTION OF HYDROXYL FREE-RADICALS IN THE REPERFUSED PRIMATE HEART, Free radical research, 21(1), 1994, pp. 19-25
Citations number
20
Categorie Soggetti
Biology
Journal title
Free radical research → ACNP
ISSN journal
10715762
Volume
21
Issue
1
Year of publication
1994
Pages
19 - 25
Database
ISI
SICI code
1071-5762(1994)21:1<19:DOHFIT>2.0.ZU;2-I
Abstract
Early reperfusion of an ischemic region can result in significant salv age of the area at risk. We show the presence of hydroxyl free radical s at the time of post ischemia reperfusion using electron paramagnetic resonance (EPR) spectroscopy in a macaque model. These free radicals may be formed as a result of reperfusion or may be an un-involved byst ander. It is possible that they may be involved in reperfusion injury.