INDUCTION OF RESPIRATION-DEFICIENT MUTANTS IN SACCHAROMYCES-CEREVISIAE BY CHELERYTHRINE

Authors
KRIVJANSKY V OBERNAUEROVA M ULRICHOVA J SIMANEK V SUBIK J
Citation
V. Krivjansky et al., INDUCTION OF RESPIRATION-DEFICIENT MUTANTS IN SACCHAROMYCES-CEREVISIAE BY CHELERYTHRINE, FEMS microbiology letters, 120(1-2), 1994, pp. 87-91
Citations number
13
Categorie Soggetti
Microbiology
Journal title
FEMS microbiology letters → ACNP
ISSN journal
03781097
Volume
120
Issue
1-2
Year of publication
1994
Pages
87 - 91
Database
ISI
SICI code
0378-1097(1994)120:1-2<87:IORMIS>2.0.ZU;2-D
Abstract
Chelerythrine and sanguinarine, two structurally related benzo/c/phena nthridine alkaloids, prevented growth of yeast cells in medium contain ing either glucose or non-fermentable carbon sources. At concentration s permitting growth of the yeast Saccharomyces cerevisiae, chelerythri ne, but not sanquinarine, induced cytoplasmic respiration-deficient mu tants. The petite clones that were analysed exhibited suppressiveness and contained different fragments of the wild-type mitochondrial genom e.