CHARACTERIZATION, STANDARDIZATION AND EXPERIENCES WITH KONE ISE FOR MG2+

The principles of a fully automated potentiometric determination of io nized magnesium in human blood serum are presented. By incorporating a magnesium selective electrode, into a commercially available six chan nel electrolyte analyzer (Microlyte 6, KONE Instruments, Finland), det ermination of the biologically-active, ionized fraction of magnesium h as been made possible. In this paper, the analytical performance of th e measurement system is presented and determination of ionized magnesi um in real patient samples is discussed with special attention to the significance of this new parameter.