EFFECTS OF A NEW ADMINISTRATION FORM OF OXYMETAZOLINE ON MAXILLARY OSTIAL PATENCY IN HEALTHY-INDIVIDUALS AND PATIENTS WITH ACUTE RHINITIS

A new administration form of the nasal decongestant oxymetazoline and its effects on maxillary ostial patency were investigated in 5 healthy individuals and 20 patients with acute rhinitis. Registration and com parison of ostial patency after administration of placebo spray and ox ymetazoline spray, placebo solution and oxymetazoline solution, were p erformed in healthy individuals. Patients with acute rhinitis were tre ated with either oxymetazoline solution or placebo solution, preceded and followed by registration of the equivalent maxillary ostial diamet er. In both studies, solution was administered with a nasal bellows co ntainer. The results suggest that the administration of oxymetazoline solution with the nasal bellows container is a more effective way of i ncreasing maxillary ostial patency in healthy individuals than oxymeta zoline spray. In patients with acute rhinitis it also seems to be a wa y of increasing maxillary ostial patency.