THE ORIGIN ISOCHROMOSOMES AND THEIR SIGNIFICANCE IN TUMORIGENESIS OF HUMAN LUNG-CANCER

Authors
FU SB LI P FENG XL LIU CX LIU QZ
Citation
Sb. Fu et al., THE ORIGIN ISOCHROMOSOMES AND THEIR SIGNIFICANCE IN TUMORIGENESIS OF HUMAN LUNG-CANCER, Cancer genetics and cytogenetics, 74(2), 1994, pp. 120-122
Citations number
7
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
74
Issue
2
Year of publication
1994
Pages
120 - 122
Database
ISI
SICI code
0165-4608(1994)74:2<120:TOIATS>2.0.ZU;2-3
Abstract
Isochromosomes related to chromosomes 1, 5, 6, 8, and 9 were frequentl y observed in 23 cases of lung cancer. Their existence in tumor cells might be nonrandom. Premature centromere separation (PCS) was found in the PGT-131 cell line of a lung cancer. It is suggested that PCS may play a role in the formation of isochromosomes in lung cancer.