DERIVATIVE CHROMOSOME, DER(17,22)(Q10,Q10), IN 2 CARCINOMAS OF THE CERVIX UTERI AND ONE OF THE SKIN

Authors
ATKIN NB BAKER MC
Citation
Nb. Atkin et Mc. Baker, DERIVATIVE CHROMOSOME, DER(17,22)(Q10,Q10), IN 2 CARCINOMAS OF THE CERVIX UTERI AND ONE OF THE SKIN, Cancer genetics and cytogenetics, 74(2), 1994, pp. 153-155
Citations number
8
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
74
Issue
2
Year of publication
1994
Pages
153 - 155
Database
ISI
SICI code
0165-4608(1994)74:2<153:DCDI2C>2.0.ZU;2-P
Abstract
In a previous study, we described 17p+ chromosomes in about 40% of car cinomas of the cervix, but it was usually not possible to identify the additional material on the short arm of the chromosome 17. Here we re port an apparently identical rearranged chromosome in two squamous cel l carcinomas of the cervix and one of the skin, in which the whole of 17p has been replaced by the long arm of a chromosome 22: der(17;22)(q 10;q10), suggesting that this rearrangement may represent a significan t step in the development of carcinomas of the cervix and other sites.