AN IMPROVED METHOD FOR BUTYRYLCHOLINESTERASE PHENOTYPING

Authors
PICHETH G FADELPICHETH C PRIMOPARMO SL CHAUTARDFREIREMAIA EA VIEIRA MM
Citation
G. Picheth et al., AN IMPROVED METHOD FOR BUTYRYLCHOLINESTERASE PHENOTYPING, Biochemical genetics, 32(3-4), 1994, pp. 83-89
Citations number
14
Categorie Soggetti
Genetics & Heredity",Biology
Journal title
Biochemical genetics → ACNP
ISSN journal
00062928
Volume
32
Issue
3-4
Year of publication
1994
Pages
83 - 89
Database
ISI
SICI code
0006-2928(1994)32:3-4<83:AIMFBP>2.0.ZU;2-J
Abstract
An improved method for the identification of butyrylcholinesterase phe notypes is proposed. It is based on modifications of a method that use s alpha-naphthyl acetate as substrate and DL-propranolol and Ro2-0683 as inhibitors. The proposed modifications make the method more rapid a nd increase the accuracy of the determinations of the phenotypes teste d (BCHE U, BCHE UF, BCHE UA, BCHE AK, BCHE AF, and BCHE A). These modi fications make the method even more adequate for population studies an d clinical routine.