COLOGNE BURN CENTER EXPERIENCES WITH GLYCEROL-PRESERVED ALLOGENEIC SKIN .1. CLINICAL-EXPERIENCES AND HISTOLOGICAL-FINDINGS (OVERGRAFT AND SANDWICH TECHNIQUE)
R. Horch et al., COLOGNE BURN CENTER EXPERIENCES WITH GLYCEROL-PRESERVED ALLOGENEIC SKIN .1. CLINICAL-EXPERIENCES AND HISTOLOGICAL-FINDINGS (OVERGRAFT AND SANDWICH TECHNIQUE), Burns, 20, 1994, pp. 190000023-190000026
Citations number
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Categorie Soggetti
Dermatology & Venereal Diseases","Emergency Medicine & Critical Care
In an effort to improve the fake of finely meshed autografts a modific
ation of the sandwich technique, as first published by Alexander et al
. (1981), was developed. In contrast to the techniques described by ot
her authors, the wound bed is sealed with fibrin glue spray after exci
sion of the burns. Widely meshed autografts are then covered with non-
meshed (only scarcely sliced) glycerolized allograft sheets, being fix
ed with staples. Patients are placed on fluidized beds and are exposed
without dressings from the fifth day onwards. Histologically and clin
ically, it can be assumed that part of the glycerolized allodermis is
incorporated. During the weeks after transplantation, a creeping subst
itution of the allodermis by autologous tissue takes place. This would
suggest a co-existence between glycerol-preserved hypo-allergenic all
ografts and auto-epidermis. Research on the definitive fate of alloder
mis in cases of sandwich grafting is continuing.