A skin bank facility is indispensable for burn care. In Holland, a ski
n bank was established in October 1976 on a national basis for economi
cal reasons. Since 1981, overcoming early rejection by innovation of e
xisting, and development of new, preservation technologies became the
main scientific objective. The immunological benefits of glycerolizati
on of skin became clear in 1983. In clinical practice, the use of glyc
erolized allograft in sandwich grafting changed this technique into a
reliable procedure. Early rejection can still be a problem, especially
in the non-immunocompromised patient. Future research projects are fo
cused on immunomodulation of the skin by chemical, physical and immuno
logical methods. Even the risk of HIV transmission is not now a drawba
ck for the use of glycerolized skin.