A FACILE ONE-POT PREPARATION OF ISOTHIOCYANATES FROM ALDOXIMES

Authors
KIM JN JUNG KS LEE HJ SON JS
Citation
Jn. Kim et al., A FACILE ONE-POT PREPARATION OF ISOTHIOCYANATES FROM ALDOXIMES, Tetrahedron letters, 38(9), 1997, pp. 1597-1598
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
9
Year of publication
1997
Pages
1597 - 1598
Database
ISI
SICI code
0040-4039(1997)38:9<1597:AFOPOI>2.0.ZU;2-D
Abstract
Isothiocyanates 2a-1 were prepared in excellent yields in a one-pot re action from aldoxime derivatives 1a-1 by successive treatment of aldox ime with N-chlorosuccinimide (NCS), thiourea, and triethylamine. The u se of HCl/DMF/Oxone system in the reaction instead of NCS was equally effective. (C) 1997 Elsevier Science Ltd.