A RAPID ASSEMBLY OF HOMOCHIRAL 2,3,4-TRISUBSTITUTED PYRROLIDINES

Authors
JONES RCF HOWARD KJ SNAITH JS
Citation
Rcf. Jones et al., A RAPID ASSEMBLY OF HOMOCHIRAL 2,3,4-TRISUBSTITUTED PYRROLIDINES, Tetrahedron letters, 38(9), 1997, pp. 1647-1650
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
9
Year of publication
1997
Pages
1647 - 1650
Database
ISI
SICI code
0040-4039(1997)38:9<1647:ARAOH2>2.0.ZU;2-Q
Abstract
The intramolecular 1,3-dipolar cycloaddition of homochiral dihydroimid azolium ylides, generated in situ, is the key reaction in a sequence t hat rapidly affords optically active 2,3,4-trisubstituted pyrrolidines suitably functionalised for further elaboration. (C) 1997 Elsevier Sc ience Ltd.