Nv. Thakor et al., MULTIWAY SEQUENTIAL HYPOTHESIS-TESTING FOR TACHYARRHYTHMIA DISCRIMINATION, IEEE transactions on biomedical engineering, 41(5), 1994, pp. 480-487
A multiway sequential hypothesis testing (M-SHT) algorithm is proposed
for simultaneous discrimination of cardiac tachyarrhythmias-supravent
ricular tachycardia (SVT) and ventricular tachycardia (VT)-from normal
sinus rhythm (NSR). The M-SHT algorithm calculates a likelihood funct
ion from atrio-ventricular delay measurements, and compares this funct
ion with thresholds derived from specified error probabilities for the
arrhythmias to be discriminated. Performance of this algorithm was ev
aluated on dual channel endocardial electrograms recorded in the cardi
ac electrophysiology laboratory. Two databases were developed, one for
development of the algorithm and another for evaluation. The M-SHT al
gorithm accurately classified 26 out of 28 NSR (2 misclassified as SVT
), 31 out of 31 cases of SVT, and 41 out of 43 VT (2 misclassified as
NSR). The average length of time taken for classification of the three
rhythms was: 3.6 s for NSR, 5.0 s for SVT, and 1.6 s for VT. Unique f
eatures of this algorithm are that acceptable error rates for each arr
hythmia are independently specified and accuracy can be traded off for
a faster detection time, and vice versa.