ANALYSIS OF THE AFFINITY OF EACH HAPTOGLOBIN POLYMER FOR HEMOGLOBIN BY 2-DIMENSIONAL AFFINITY ELECTROPHORESIS

Authors
OKAZAKI T YANAGISAWA Y NAGAI T
Citation
T. Okazaki et al., ANALYSIS OF THE AFFINITY OF EACH HAPTOGLOBIN POLYMER FOR HEMOGLOBIN BY 2-DIMENSIONAL AFFINITY ELECTROPHORESIS, Clinica chimica acta, 258(2), 1997, pp. 137-144
Citations number
8
Categorie Soggetti
Medical Laboratory Technology",Biology
Journal title
Clinica chimica acta → ACNP
ISSN journal
00098981
Volume
258
Issue
2
Year of publication
1997
Pages
137 - 144
Database
ISI
SICI code
0009-8981(1997)258:2<137:AOTAOE>2.0.ZU;2-B
Abstract
Using polyacrylamide gel electrophoresis we have often encountered a d ecrease in the high molecular weight polymers of haptoglobin 2-1 in th e serum of patients after transfusion and with hemolytic diseases. Usi ng two-dimensional affinity electrophoresis we have attributed this ph enomenon to the high affinity of high molecular weight polymers of the haptoglobin 2-1 for hemoglobin. (C) 1997 Elsevier Science B.V.