Nigrosin binds to proteins yielding a dark blue complex. This reaction
is used for detecting low protein concentrations in urine by applying
spots of urine to cellulose acetate strips which are coloured by nigr
osin. The intensity of coloured spots remaining after washing of the s
trips indicates protein concentration. With a cut-off at 50 mg protein
/l, the test offers an excellent possibility for first line screening
for microalbuminuria at lowest cost. (C) 1997 Elsevier Science B.V.