KETOPROFEN, A NONSTEROIDAL, ANTIINFLAMMATORY DRUG, HAS ANTIMICROBIAL ACTIVITY AGAINST DERMATOPHYTES

Authors
CHOWDHURY B MUKHOPADHYAY S
Citation
B. Chowdhury et S. Mukhopadhyay, KETOPROFEN, A NONSTEROIDAL, ANTIINFLAMMATORY DRUG, HAS ANTIMICROBIAL ACTIVITY AGAINST DERMATOPHYTES, Medical science research, 25(2), 1997, pp. 109-110
Citations number
6
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Medical science research → ACNP
ISSN journal
02698951
Volume
25
Issue
2
Year of publication
1997
Pages
109 - 110
Database
ISI
SICI code
0269-8951(1997)25:2<109:KANADH>2.0.ZU;2-P
Abstract
The effect of ketoprofen on growth in vitro of eight fungal species an d Candida albicans was tested. Ketoprofen showed significant antifunga l activity against dermatophytes. The activity was affected by pH, bei ng greater at values below pH 7.0. In this respect, ketoprofen is comp aratively more efficient than two well known and medically used antifu ngal compounds, benzoic acid and salicyclic acid. These in vitro resul ts suggest the possibility of medical applications of ketoprofen.