Stainless steel plugs coated with and without Al2O3, TiO2 and Nb2O5 we
re inserted into canine femora in order to develop a methodology of ra
pid identification of appropriate specimens for deeper analysis of imp
lant-bone interfaces. This approach is especially meaningful in areas
where research funds are scarce. After a maximum follow-up period of 5
2 wk, bone segments containing plugs were radiographed using conventio
nal techniques, high resolution techniques (which allowed a good preli
minary evaluation) and microradiography. Analysis by X-ray fluorescenc
e spectrometry indicated release of the materials by the implants. Mic
rodensitometry of the microradiographs allowed a precise thickness det
ermination of the tissue formed around the implants.