HOST-BACTERIAL INTERACTIONS IN THE PATHOGENESIS OF GROUP-B STREPTOCOCCAL INFECTIONS

Authors
TAMURA GS RUBENS CE
Citation
Gs. Tamura et Ce. Rubens, HOST-BACTERIAL INTERACTIONS IN THE PATHOGENESIS OF GROUP-B STREPTOCOCCAL INFECTIONS, Current opinion in infectious diseases, 7(3), 1994, pp. 317-322
Citations number
NO
Categorie Soggetti
Infectious Diseases
Journal title
Current opinion in infectious diseases → ACNP
ISSN journal
09517375
Volume
7
Issue
3
Year of publication
1994
Pages
317 - 322
Database
ISI
SICI code
0951-7375(1994)7:3<317:HIITPO>2.0.ZU;2-Z
Abstract
Group B streptoococcal invasive disease occurs as group B strepococci adhere to, and then intracellularly invade, respiratory epithelial and endothelial cells and enter the blood stream. The group B streptococc i produce a capsule which inhibits complement deposition and phagocyto sis. Bacterial-surface components then induce the release of eicosanoi ds and tumor necrosis factor-alpha, which mediate aspects of the sepsi s syndrome.