CYCLOHEXYLIDENEACETYL ISOTHIOCYANATE - PRECURSOR FOR THE SYNTHESIS OF1,3-THIAZASPIROCYCLOALKANES AND 1,3-DIAZASPIROCYCLOALKANES

Authors
TOROK M DZURILLA M KUTSCHY P IMRICH J DANIHEL I RADEMACHER P BANDMANN H
Citation
M. Torok et al., CYCLOHEXYLIDENEACETYL ISOTHIOCYANATE - PRECURSOR FOR THE SYNTHESIS OF1,3-THIAZASPIROCYCLOALKANES AND 1,3-DIAZASPIROCYCLOALKANES, Collection of Czechoslovak Chemical Communications, 59(5), 1994, pp. 1203-1210
Citations number
14
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
59
Issue
5
Year of publication
1994
Pages
1203 - 1210
Database
ISI
SICI code
0010-0765(1994)59:5<1203:CI-PFT>2.0.ZU;2-B
Abstract
The N-(4-substituted phenyl)-N'-cyclohexylideneacetylthioureas IIa - I If were readily prepared by the reaction of cyclohexylideneacetyl isot hiocyanate I with 4-substituted anilines. They were cyclized to the 2- (4-substituted phenylimino)-4-oxo-1,3-thiazaspiro[5.5]undecanes IIIa - IIIe in the presence of boron trifluoride etherate and to the 1-(4-su bstituted enyl)-4-oxo-2-thioxo-1,3-diazaspiro[5.5]-undecanes IVa, IVc - IVf in alkaline medium.