Mk. Toppozada et al., ORAL OR VAGINAL MISOPROSTOL FOR INDUCTION OF LABOR, International journal of gynaecology and obstetrics, 56(2), 1997, pp. 135-139
Objective: To compare vaginal versus oral misoprostol for induction of
labor. Method: Induction of labor was carried out in 40 women near te
rm in two equal and randomized groups (according to a computer generat
ed table) using misoprostol. Group I received vaginal misoprostol (100
mu g) every 3 h while group II patients were given the same dose via
the oral route. The dose was doubled if no response was detected under
continuous cardiotocographic (CTG) tracings. Result: The vaginal rout
e of administration induced a higher success rate in a shorter time in
terval using a lower dose but was associated with more abnormal FHR pa
tterns and instances of uterine hyperstimulation. Conclusion: It is re
commended to use the vaginal approach with cardiotocographic monitorin
g. (C) 1997 International Federation of Gynecology and Obstetrics.