The purpose of this study was to explore the relationship between the
loss of protective pressure sensation in the foot and the formation of
plantar calluses, two well-known precursors of plantar ulceration, in
adults with diabetes referred to an outpatient diabetes education pro
gram. Pressure sensation testing was performed using Semmes-Weinstein
monofilaments. Foot inspection included the identification and measure
ment of plantar calluses. Using the Wilcoxon Rank Sum test, groups cat
egorized as sensitive (n=67) and insensitive (n=35) were compared on c
allus formation. The groups had equivalent numbers, areas, and thickne
ss of calluses. The high prevalence of calluses in both sensitive and
insensitive groups suggests that additional factors such as age-relate
d changes in the foot and routine footwear must be included in risk as
sessment of the diabetic foot and in consideration of preventive inter
ventions.