14-EPIDIHYDROCOCHLIOQUINONE-B AND 14-EPICOCHLIOQUINONE-B, ANTIBIOTICSFROM FERMENTATIONS OF THE ASCOMYCETE NEOBULGARIA-PURA - STRUCTURE ELUCIDATION AND EFFECTS ON PLATELET-AGGREGATION

Authors
LORENZEN K ANKE T ANDERS U HINDERMAYR H HANSSKE F
Citation
K. Lorenzen et al., 14-EPIDIHYDROCOCHLIOQUINONE-B AND 14-EPICOCHLIOQUINONE-B, ANTIBIOTICSFROM FERMENTATIONS OF THE ASCOMYCETE NEOBULGARIA-PURA - STRUCTURE ELUCIDATION AND EFFECTS ON PLATELET-AGGREGATION, Zeitschrift fur Naturforschung. C, A journal of biosciences, 49(5-6), 1994, pp. 312-320
Citations number
26
Categorie Soggetti
Biology
Journal title
Zeitschrift fur Naturforschung. C, A journal of biosciences → ACNP
ISSN journal
09395075
Volume
49
Issue
5-6
Year of publication
1994
Pages
312 - 320
Database
ISI
SICI code
0939-5075(1994)49:5-6<312:1A1A>2.0.ZU;2-4
Abstract
14-Epicochlioquinone B (1) and 14-epidihydrocochlioquinone B (2) were isolated from submerged cultures of Neobulgaria pura (Pers. ex Fr.) Pe trak. 14-Epicochlioquinone B is a potent inhibitor of human and bovine platelet aggregation stimulated by different inducers. 14-Epidihydroc ochlioquinone B does not inhibit the aggregation of platelets. In addi tion, both 1 and 2 exhibited cytotoxic and antimicrobial activities.