OBJECTIVE: To better understand the life expectancy of patients who ha
ve an abnormal videofluoroscopic swallowing study. DESIGN: Retrospecti
ve cohort study. The common starting point was the time of the severel
y abnormal swallowing study. Hospital charts were reviewed for clinica
l variables of potential prognostic significance by reviewers blinded
to the outcome of interest, survival time. SETTING: A university-affil
iated, community teaching hospital. PATIENTS: One hundred forty-cine h
ospitalized patients who were deemed nonoral feeders based on their sw
allowing study, Patients excluded were those with head, neck, or esoph
ageal cancer, or those undergoing a thoracotomy procedure. MEASUREMENT
S AND MAIN RESULTS: Clinical and demographic variables and time until
death or censoring were measured, Overall I-year mortality was 62%. Mu
ltivariable Cox proportional hazards analyses identified four variable
s that independently predicted death: advanced age, reduced serum albu
min concentration, disorientation to person, and higher Charlson comor
bidity score, Eighty patients (54%) subsequently underwent placement o
f a percutaneous endoscopic gastrostomy (PEG) tube after their swallow
ing study. CONCLUSIONS: Mortality is high in patients with severely ab
normal swallowing studies, Common clinical variables can be used to id
entify groups of patients with particularly poor prognoses. This infor
mation may help guide discussions regarding possible PEG placement.