MALFORMATIONS OF THE SEPTUM-PELLUCIDUM - 2 DISTINCTIVE CASES IN ASSOCIATION WITH SCHIZOPHRENIA

Authors
WOLF SS HYDE TM WEINBERGER DR
Citation
Ss. Wolf et al., MALFORMATIONS OF THE SEPTUM-PELLUCIDUM - 2 DISTINCTIVE CASES IN ASSOCIATION WITH SCHIZOPHRENIA, Journal of psychiatry & neuroscience, 19(2), 1994, pp. 140-144
Citations number
25
Categorie Soggetti
Psychiatry
Journal title
Journal of psychiatry & neuroscience → ACNP
ISSN journal
11804882
Volume
19
Issue
2
Year of publication
1994
Pages
140 - 144
Database
ISI
SICI code
1180-4882(1994)19:2<140:MOTS-2>2.0.ZU;2-F
Abstract
Two patients with schizophrenia had markedly abnormal neuroimaging stu dies; one was found to have a large, cystic cavum vergae, while the ot her demonstrated complete agenesis of the septum pellucidum with a mon oventricular system. The increased prevalence of developmental abnorma lities of midline forebrain structures in patients with schizophrenia suggests that dysgenesis of these structures may be contributory to th e neurobiology of schizophrenia and other psychotic disorders.