IMMUNODEPRESSION INDUCED BY CARBAMAZEPINE ADMINISTRATION IS MEDIATED BY CD-8-CELLS( SPLEEN T)

Authors
ANDRADEMENA CE
Citation
Ce. Andrademena, IMMUNODEPRESSION INDUCED BY CARBAMAZEPINE ADMINISTRATION IS MEDIATED BY CD-8-CELLS( SPLEEN T), International journal on tissue reactions, 18(2-3), 1996, pp. 81-85
Citations number
15
Categorie Soggetti
Cell Biology
Journal title
International journal on tissue reactions → ACNP
ISSN journal
02500868
Volume
18
Issue
2-3
Year of publication
1996
Pages
81 - 85
Database
ISI
SICI code
0250-0868(1996)18:2-3<81:IIBCAI>2.0.ZU;2-X
Abstract
The values observed in this series of experiments showed that CD 8+ sp leen T cells obtained from 15-mg/kg carbamazepine (CBZ)-treated donor mice were capable of diminishing both humoral and cellular immune resp onses of normal spleen cells when transferred into lethally irradiated recipient animals, Immune responses were evaluated by enumeration of direct and indirect plaque-forming spleen cells (PFC) and by the delay ed-type hypersensitivity reaction (DTH) to sheep red blood cells.