CLUSTER OF CYTOCHROME-P450 GENES ON THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER

Authors
FROLOV MV ALATORTSEV VE
Citation
Mv. Frolov et Ve. Alatortsev, CLUSTER OF CYTOCHROME-P450 GENES ON THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER, DNA and cell biology, 13(6), 1994, pp. 663-668
Citations number
29
Categorie Soggetti
Cytology & Histology",Biology,"Genetics & Heredity
Journal title
DNA and cell biology → ACNP
ISSN journal
10445498
Volume
13
Issue
6
Year of publication
1994
Pages
663 - 668
Database
ISI
SICI code
1044-5498(1994)13:6<663:COCGOT>2.0.ZU;2-L
Abstract
A new cytochrome P450 gene was found within the wapl-prune genetic reg ion of the Drosophila melanogaster X chromosome. It encodes a putative cytochrome P450 of subfamily 4D and has been designated CYP4D2. CYP4D 2 has a complex exon-intron structure. Both the heme-binding motif and a region diagnostic for family 4 are not interrupted by introns. CYP4 D2 lies 20 kb proximal to the previously described CYP4DI gene (Gandhi et al., 1992). In addition to CYP4DI and CYP4D2, two other DNA fragme nts homologous to P450 genes are detected within the wapl-prune region .