POTENTIAL USE OF MICROENCAPSULATION FOR SUSTAINED DRUG-DELIVERY TO THE RESPIRATORY-TRACT

Authors
HAGHPANAH M MARRIOTT C MARTIN GP
Citation
M. Haghpanah et al., POTENTIAL USE OF MICROENCAPSULATION FOR SUSTAINED DRUG-DELIVERY TO THE RESPIRATORY-TRACT, Journal of aerosol medicine, 7(2), 1994, pp. 185-188
Citations number
NO
Categorie Soggetti
Public, Environmental & Occupation Heath
Journal title
Journal of aerosol medicine → ACNP
ISSN journal
08942684
Volume
7
Issue
2
Year of publication
1994
Pages
185 - 188
Database
ISI
SICI code
0894-2684(1994)7:2<185:PUOMFS>2.0.ZU;2-9
Abstract
Microencapsulation has long been regarded as a means of achieving sust ained drug delivery. In these studies, a spray drying technique was us ed to produce salbutamol-loaded albumin microparticles with a view to formulating a controlled release system to be used in respiratory drug delivery. Encapsulation efficiencies (40-60 % w/w) obtained using thi s technique compared very favourably with those obtained using emulsif ication procedures (1-2 % w/w).