HIGH-DOSE RECOMBINANT-HUMAN-ERYTHROPOIETIN AND LOW-DOSE CORTICOSTEROIDS FOR TREATMENT OF ANEMIA IN PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA

Authors
BOURANTAS K
Citation
K. Bourantas, HIGH-DOSE RECOMBINANT-HUMAN-ERYTHROPOIETIN AND LOW-DOSE CORTICOSTEROIDS FOR TREATMENT OF ANEMIA IN PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA, Acta haematologica, 91(2), 1994, pp. 62-65
Citations number
18
Categorie Soggetti
Hematology
Journal title
Acta haematologica → ACNP
ISSN journal
00015792
Volume
91
Issue
2
Year of publication
1994
Pages
62 - 65
Database
ISI
SICI code
0001-5792(1994)91:2<62:HRALC>2.0.ZU;2-C
Abstract
Three patients with paroxysmal nocturnal hemoglobinuria (PNH) and seve re anemia were treated with high-dose recombinant human erythropoietin (rHEpo) and low-dose corticosteroids. During therapy their hemoglobin levels gradually improved and no blood transfusions were required. Ne ither rHEpo nor corticosteroids caused any side effects. This study sh ows that high rHEpo and low corticosteroid doses may improve the anemi a of PNH patients.