CONVERSION OF RACEMIC 2-HYDROXYMETHYL[5]THIAHETEROHELICENE INTO A SINGLE ENANTIOMER ON THE UPTAKE BY BOVINE SERUM-ALBUMIN

Authors
YAMADA K ISHII R NAKAGAWA H KAWAZURA H
Citation
K. Yamada et al., CONVERSION OF RACEMIC 2-HYDROXYMETHYL[5]THIAHETEROHELICENE INTO A SINGLE ENANTIOMER ON THE UPTAKE BY BOVINE SERUM-ALBUMIN, Journal of the Chemical Society, Chemical Communications, (13), 1994, pp. 1521-1522
Citations number
9
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
13
Year of publication
1994
Pages
1521 - 1522
Database
ISI
SICI code
0022-4936(1994):13<1521:COR2IA>2.0.ZU;2-2
Abstract
Racemic droxymethylthieno[3,2-e:4,5-e']di[1]benzothiophene with a labi le helical structure was converted into a (P) enantiomer upon uptake b y bovine serum albumin, in which the existence of two substrate-bindin g sites with a distinct ability to recognize chirality was revealed.